# To make vancomycin effective against vancomycin-resistant MRSA, the starred carbon shown here is converted to an...

###### Question:

To make vancomycin effective against vancomycin-resistant MRSA, the starred carbon shown here is converted to an amidine, yielding a vancomycin derivative. When the normal structure of vancomycin is converted to its amidine derivative, the starred carbon undergoes:

a) a reduction in oxidation state but no change in hybridization.

b) a change in hybridization but no change in oxidation state

c) both a reduction in oxidation state and a change in hybridization.

d) neither a reduction in oxidation state nor a change in hybridization.

The answer is: neither a reduction in oxidation state nor a change in hybridization; How did they get the oxidation state of carbon?

O R NH CH NH * 3 NI I C)

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