Answers
A. 
B. Out of 4 children, chances that Wanda is a carrier, are 25%. But if we take only female children into consideration, than there are 50% chances of Wanda being a carrier.
(Shown in the figure above).
C. If Wanda is a carrier, XaX, then she will produce two gametes, Xa and X, each with an equal probability of 50%. We know that a son inherits X chromosome from his mother and Y from his father. So, Wanda's son can be either XaY (affected) or XY (normal), both genotypes with an equal probability of 50%.
D. This is because, women have 2 copies of X chromosomes and males are hemizygous for X.
Any recessive mutation would affect males more than females because one mutated X chromosome is enough in males to cause disease whereas, 2 mutated X chromosomes are required to cause disease in females. This is possible only when the father of a female is has X linked recessive disorder and her mother is atleast carrier. This seems to be very unlikely. Hence, females are not seen to be affected in this case.
Please rate.
Menkes olisease 11 2xy xay Wanda 7 |2 4 3 4 56 Xay xay wanda Parcents ax (1-3) y (-2) X Y - cauer 114-25/. xax - deceased 7- 4-25/.
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Ay 14-25. mmal t - XX /4-25 Y OR
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