# Pedigree 8. The Addams family knows of three relatives who had Menkes disease, and X-linked recessive...

###### Question:

pedigree
8. The Addams family knows of three relatives who had Menkes disease, and X-linked recessive disorder in which a child does not grow, has brain degeneration, and dies by age two. Affected children have peculiar white stubby hair. Wanda Addams is hesitant about having children because her two sisters have each had sons who died from Menkes discase. Her mother had a brother who died of the condition, too. The pedigree for the family is shown below. A. Fill in the symbols for the family members who must be carriers of Menkes disease. B. What is the chance that Wanda (III-7) is a carrier? C. If Wanda is a carrier, what is the chance that a son of hers would inherit the disease? D. Why don't any women in the family have Menkes discase? 3 6 5 IV Menkes disease

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