1 answer

In order to convert to the active state, a G protein must catalyze the addition of...

Question:

In order to convert to the active state, a G protein must catalyze the addition of a phosphate group to the GDP molecule boun

In order to convert to the active state, a G protein must catalyze the addition of a phosphate group to the GDP molecule bound to the protein. O True O False

Answers

True

G proteins(made up of 3 subunits-G alpha,G beta and G gamma) associated with the inner side of membrane and transmembrane receptors of hormones also known as G protein coupled receptors(GPCRs) are called G proteins because they bind the GDP and GTP.GDP remain present in the binding site(inactive) of G alpha so whenever any hormone comes in contact with GPCR there is an allosteric structural change in the G alpha causing the release of GDP then replaced by GTP which in turn activates G alpha.Thereafter activated G alpha seprate itself from G beta and G gamma and actiavtes the another effector molecule which will convey the message of the respective hormone.

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