## Answers

Sore throat

Methotrexate medicine lowers the ability to fight infections and cause severe infection and it worse and causes illness like fever, chills, cough, and persistent sore throat. Tell the doctor immediately if these signs are appearing.

Associate problem include diarrhea, anemia, dark urine, nausea, vomiting, stomach pain, yellow eyes, and skin, bleeding, enlarge lymph nodes, bone pain, dry mouth and muscle weakness, headache, neck stiffness, irregular heartbeat, rash, itching, and swelling of face, tongue and lips, dizziness and trouble breathing.

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